| Autor: |
Gill, Ryan, Warnecke, Tanya, Barghetti, Andrea, Poulsen, Line |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Gill, R, Warnecke, T, Barghetti, A & Poulsen, L Apr. 08 2021, Crispr systems with engineered dual guide nucleic acids, Patent No. WO2021067788 . |
| Popis: |
The present invention relates to an engineered Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) system comprising engineered dual guide nucleic acids (e.g., RNAs) capable of activating a CRISPR- Associated (Cas) nuclease, such as a type V-A Cas nuclease. Also provided are methods of targeting, editing, and/or modifying a nucleic acid using the engineered CRISPR system, and compositions and cells comprising the engineered CRISPR system. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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