Refractory facial Darier's disease treated with daylight photodynamic therapy

Autor: Morelló-Vicente, A. (Ana), Antoñanzas, J. (Javier), Estenaga, Á. (Ángela), Oteiza-Rius, I. (Inés), Salido-Vallejo, R. (Rafael), España, A. (Agustín)
Jazyk: Spanish; Castilian
Rok vydání: 2022
Předmět:
Popis: Darier’s disease (DD) is an infrequent autosomal dominant skin disorder caused by a mutation of the ATP2A2 gene on chromosome 12 [1]. Mutations in this gene result in abnorma-lities in keratinocyte cell-cell adhesion producing an alterati-on of the keratinization of the skin, which clinically presents with dyskeratotic papules mostly affecting seborrheic and in-tertriginous areas. Palmoplantar and nail involvement is often present [1–3]. As a wide range of treatments have been propo-sed for this skin disorder with different results, the manage-ment of this disease is still a challenge for the dermatologist.
Databáze: OpenAIRE
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