MHC evolution in the Neotropical the Midas cichlid
| Autor: | Lozano Martín, Carlos, Bracamonte, Seraina E., Barluenga, Marta |
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| Rok vydání: | 2023 |
| Popis: | Este seminario tuvo lugar en Las Caldas (Oviedo) del 18 al 20 de enero de 2023 The antagonistic interaction between hosts and parasites is recognized as one major driver of animal diversification. Parasites impose strong selective pressures on their hosts, which induce immune responses that have the potential to cause local adaptation in host populations, and ultimately diversification and even speciation. The adaptive immune response is partly mediated by the Major Histocompatibility Complex (MHC), a gene family which represents one of the most variable genomic regions in vertebrates. MHC variability is generated, to some extent, by parasite diversity and maintained by balancing selection resulting from the interplay between MHC and parasites. Hosts inhabiting alternative habitats are exposed to different parasite communities, and these contrasting pressures should generate MHC heterogeneity and local signatures across host populations. Here we studied the role of host-parasite interactions in generating diversity in the recent adaptive radiation of The Midas cichlid fish (Amphilophus spp.) in the Nicaraguan lakes. Sympatric Midas cichlid species have evolved in parallel in different lakes adapting to exploit alternative habitats and trophic resources. Parallelism is also reflected in phenotypic variation affecting body shape and trophic structures. We already recognized that there is a lake-specific MHC signature. Here we analyzed MHC variation across Midas cichlid species and populations and evaluated MHC signatures associated to parallel ecotypes. Moreover, we analyzed temporal variability of MHC population signatures. We compare this data with parasite communities and their temporal variability |
| Databáze: | OpenAIRE |
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