A commercially available and user-friendly catalyst for hydroamination reactions under technical conditions
| Autor: | Zelenay, B, Munton, P, Tian, X, Diez-Gonzalez, S |
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| Přispěvatelé: | The Royal Society |
| Rok vydání: | 2019 |
| Předmět: |
Science & Technology
0304 Medicinal and Biomolecular Chemistry TERMINAL ALKYNES N-H Organic Chemistry Chemistry Organic AROMATIC-AMINES Heterocycles INTERMOLECULAR HYDROAMINATION 0305 Organic Chemistry Hydroamination ONE-POT SYNTHESIS Chemistry EFFICIENT SYNTHESIS Alkynes ANTI-MARKOVNIKOV HYDROAMINATION Physical Sciences INTRAMOLECULAR HYDROAMINATION AZA-MICHAEL ADDITION Allenes ASYMMETRIC-SYNTHESIS Copper |
| Popis: | The activity of a simple, commercially available copper salt, [Cu(NCMe)4](BF4) in intramolecular hydroamination reactions of alkynes and allenes is presented. Reactions were successfully carried out in technical acetonitrile in the presence of air. While attempts of alkene hydroamination failed, this catalysts was also found active in intermolecular aza‐Michael reactions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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