Study of a medical device to treat aortic dissection with Finite Element Analysis
| Autor: | Casero Sánchez, Alba |
|---|---|
| Přispěvatelé: | Carmona Flores, Manuel, Soudah Prieto, Eduardo |
| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: |
Aorta diseases
Finite element method Programari lliure Malalties cardiovasculars Heart diseases Bachelor's theses Cardiology Malalties de l'aorta Mètode dels elements finits Treballs de fi de grau Open source software Malalties del cor Cardiologia Cardiovascular diseases Enginyeria biomèdica Biomedical engineering |
| Popis: | Treballs Finals de Grau d'Enginyeria Biomèdica. Facultat de Medicina i Ciències de la Salut. Universitat de Barcelona. Curs: 2022-2023. Tutor/Director: Carmona Flores, Manuel, Soudah Prieto, Eduardo The aortic dissection is a cardiovascular disease that results from the rupture of the inner layer of the aorta. Type B aortic dissections commonly become a chronic disease with a high long-term morbidity and mortality rates. Current treatments include open surgery repair and thoracic endovascular aortic repair (TEVAR). However, new non-invasive treatments are being developed that favour the own regeneration of the tissue, avoiding the permanent presence of a foreign device in the body. This project focuses on the understanding of a new treatment with a medical device, an aortic patch, by in silico testing. The goal is to determine the performance of the patch in a simulated aortic dissection and then compare it with the current treatment with the stent graft (TEVAR), to determine if it would avoid the hypertension that can be caused by the stent. To do the first part, it was created a model of the aortic dissection, but due to complications with the simulation, this part of the project couldn’t be finished, and the performance of the patch in the aortic dissection couldn’t be determined. To do the second part three models were created: healthy aorta, aortic dissection with stent graft and aortic dissection with patch. A transient simulation was run for the three models and the pressure waveform was analyzed. The results show that the pressure in the stent graft model is higher, and the patch has a similar response to the healthy aorta. However, all the models presented hypertension (including the healthy aorta) and the differences between the models are too small to be concluding, so it cannot be assured that the patch is a better option than the stent graft to avoid causing hypertension in the aortic dissection treatment. |
| Databáze: | OpenAIRE |
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