Acute Disseminated Encephalomyelitis Mimicking Acute Meningoencephalitis

Autor: Reza Ashrafi Mahmoud, Amirkashani Davood, Hirbod-Mobarakeh Armin, Yaghmaei Bahareh, Tavassoli Alireza, Manafi Farzad, Rezaei Nima
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Acta clinica Croatica
Volume 52.
Issue 4.
ISSN: 1333-9451
0353-9466
Popis: Acute disseminated encephalomyelitis is an inflammatory demyelinating disease of the central nervous system that usually occurs following an antecedent infection or vaccination. Children and young adults are predominantly affected, but it has low incidence in children younger than 3 years. The disease manifests with a wide range of neurological abnormalities and a variable combination of fever, headache, meningism, convulsion and cranial nerve palsies, and there are no pathognomonic clinical or laboratory findings. So, establishment of definitive diagnosis is challenging in infants. This challenge may result in delayed diagnosis and consequently delayed treatment of acute disseminated encephalomyelitis, which may cause permanent neurological disability. Herein, we report an infant with acute disseminated encephalomyelitis, who mimicked the symptoms of meningoencephalitis and the correct diagnosis and treatment were delayed till the development of a severe phase of the disease.
Akutni diseminirani encefalomijelitis je upalna demijelinizirajuća bolest središnjega živčanog sustava koja se najčešće javlja nakon prethodne infekcije ili cijepljenja. Uglavnom zahvaća djecu i mlađe odrasle osobe, ali ima nisku incidenciju u djece mlađe od tri godine. Bolest se očituje širokom lepezom neuroloških nenormalnosti i različitim kombinacijama groznice, glavobolje, meningizma, konvulzija i paralize kranijskih živaca, a nema nikakvih karakterističnih kliničkih ili laboratorijskih nalaza. Stoga je kod dojenčadi postavljanje konačne dijagnoze vrlo zahtjevno, što može dovesti do kašnjenja u dijagnozi i posljedično zakašnjelog liječenja, a to opet može uzrokovati trajne neurološke posljedice. Ovdje prikazujemo slučaj dojenčeta s akutnim diseminiranim encefalomijelitisom, kod kojega su simptomi bili slični simptomima meningoencefalitisa pa je zakašnjelo postavljanje točne dijagnoze, a time i liječenje dovelo do razvoja teže faze bolesti.
Databáze: OpenAIRE