Clinical picture, haematological parameters and pathomorphological findings in fattening chickens after application of a lethal quantity of 32P

Autor: Miljenko Šimpraga, Marina Tišljar, Željko Grabarević, Marinko Vilić, Petar Kraljević
Jazyk: angličtina
Rok vydání: 2006
Předmět:
Zdroj: Veterinarski arhiv
Volume 76
Issue 6
ISSN: 1331-8055
0372-5480
Popis: Due to its quality and relatively low price as a result of a simple and short production cycle, poultry meat occupies a very high position in the consumption of foodstuffs of animal origin. It is just because of such simple and rapid production that, under the circumstances of larger-scale radioactive contamination, poultry meat might become the main source of protein of animal origin. This fact, as well as the fact that no investigation into the effects of radioactive phosphorus (32P) on fattening chickens has been conducted so far, induced us to investigate the impact of a lethal quantity of this isotope on chickens at slaughter age. The investigation was performed on chickens, hybrids of the Jata heavy breeds of both sexes, aged 50 days and with a mass ranging from 1500 to 2000 g. The experiment was based on the application of radioactive phosphorus 32P at 333 MBq/kg of body mass. Test animals were clinically examined, blood samples were taken for haematological analysis and, immediately after death, dissection and pathohistological examination were performed. Based on the obtained results it was concluded that radioactive phosphorus 32P, when applied to 50-day-old chickens of the Jata heavy breed at 333 MBq/kg of body mass, causes: 1) anaemia, manifested by a decrease in erythrocyte count on the 5th day and decreased and haematocrit values 7 days post-contamination; 2) leukopoenia, in a decrease in lymphocyte count on the 1st day; decreased eosinophil count on the 3rd day, and decreased heterophil count 5 days post-contamination; 3) thrombocytopoenia, on the 5th day post-contamination; 4) onset of clinical signs of radiation sickness on the 6th day, and death of all contaminated animals on the 9th and 10th days post-contamination contamination. Pathoanatomic examination of dead animals revealed dotted bleeding sites on heart and mucous membrane of digestive tract, as well as changes in parenchymal organs. Pathohistological examination of tissues and organs confirmed the findings of pathoanatomic examinations, which indicated the changes caused by radioactive radiation.
Meso peradi po svojoj kvaliteti i relativno niskoj cijeni, zbog jednostavnog i kratkog proizvodnog ciklusa, zauzima vrlo visoko mjesto u prehrani namirnicama životinjskoga podrijetla. U okolnostima radioaktivne kontaminacije meso peradi, upravo zbog jednostavne i brze proizvodnje, može postati glavni izvor bjelančevina životinjskoga podrijetla. Navedene činjenice, te činjenica da ni do danas nije načinjeno istraživanje o učinku radioaktivnog 32P u tovnih pilića, potaknule su nas da istražimo utjecaj letalne količine ovoga radionuklida u peradi u dobi za klanje. Istraživanje je obavljeno na pilićima teške pasmine »Jata« oba spola, starosti 50 dana i tjelesne mase od 1500 i 2000 g. Pilićima je apliciran radiaoktivni 32P u količini od 333 MBq po kilogramu tjelesne mase. Pokusne su životinje klinički pregledane, a krv za hematološku analizu uzimana je iz krilne vene. Neposredno nakon smrti životinja učinjena je razudba i patohistološka pretraga. Dobiveni rezultati pokazali su da 32P, apliciran pilićima teške pasmine »Jata« 50. dana starosti u količini od 333 MBq/kg tjelesne mase uzrokuje: 1) anemiju koja se očituje padom broja eritrocita 5. dana nakon radioaktivne kontaminacije te padom hematokrita koji se očituje 7. dana nakon radioaktivne kontaminacije; 2) leukopeniju uzrokovanu padom broja limfocita 1. dana nakon radioaktivne kontaminacije, smanjenjem broja eozinofila 3. dana nakon radioaktivne kontaminacije i smanjenjem broja heterofila 5. dana nakon radioaktivne kontaminacije; 3) trombocitopeniju 5. dana nakon radioaktivne kontaminacije; 4) pojavu kliničkih znakova radijacijske bolesti 6. dana i smrt svih kontaminiranih životinja 9. i 10. dana nakon radioaktivne kontaminacije. Patohistološka pretraga tkiva i organa sukladna je patoanatomskom nalazu.
Databáze: OpenAIRE
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