EOZINOFILNI GASTROENTERITIS I PLEURITIS S ASCITESOM I PLEURALNIM IZLJEVOM NEPOZNATE ETIOLOGIJE: DIJAGNOSTIČKI PROBLEM

Autor: Miodrag Milojković, Milanka Mrčela, Mirjana Rubin, Dimitrije Milojković
Jazyk: chorvatština
Rok vydání: 2010
Předmět:
Zdroj: Gynaecologia et perinatologia : journal for gynaecology, perinatology, reproductive medicine and ultrasonic diagnostics
Volume 19
Issue 1
ISSN: 1330-0091
Popis: Prikazana je pacijentica s eozinofilnim gastroenteritisom i pleuritisom kompliciranim ascitesom i pleuralnim izljevom te visokom razinom CA 125 u serumu. Bolesnica je operirana zbog sumnje na uznapredovali malignom jajnika. Osim osjećaja nadutosti, povećanja obima trbuha i opstipacije pacijentica nije imala drugih tegoba. U perifernoj krvi je nađeno 61,0% eozinofila i razina CA 125 u serumu 322,0. Tijekom obrade nije se mogao naći uzrok eozinofilije, broj eozinofila u perifernoj krvi je padao bez ikakve terapije, a razina CA 125 je rasla. U cilju definitivne dijagnoze učinjena je laparotomija i biopsija želuca i crijeva te tako dokazan eozinofilni gastroenteritis. Došlo je do spontane normalizacije broja eozinofila u krvi, razine CA 125 te povlačenja ascitesa i pleuralnog izljeva. Pacijentica je kontrolirana kroz šest godina i nije bilo recidiva bolesti ni pojave nekih drugih težih bolesti. Zaključak. Radilo se o eozinofilnom gastroenteritisu i pleuritisu, nepoznate etiologije, sa spontanim izlječenjem i bez recidiva u šest godina praćenja. Dijagnoza bolesti bila je otežana zbog atipičnog tijeka, sa spontanim izlječenjem.
The paper presents a case of eosinophilic gastroenteritis and pleurisy, complicated with ascites and pleural exudate, with high level of CA 125 in the serum. The patient underwent a surgery due to a suspected ovarial cancer. The patient complained of bloating and constipation but did not experience any other problems. Blood analysis showed 61.0% of eosinophilia in peripheral blood and 322.0 level of CA 125 in the serum. In spite of all examinations we could not detect the cause of eosinophilia and the number of eosinophils in the peripheral blood dropped without any therapy, whereas level of CA 125 kept increasing. In order to diagnose the right condition, the patient had laparotomy, stomach and bowel biopsy performed, which confirmed eosinophilic gastroenteritis. The laparotomy and bowel biopsy were done, confirming the diagnosis of eosinophilic gastroenteritis. Within due course of time the number of eosinophils in blood normalized spontaneously and so did the level of CA 125, ascites and pleurisy disappeared. The patient was closely observed for six years and did not experienced any relapse or any other serious health problems. Conclusion. The paper describes a case of eosinophilic gastroenteritis and pleurisy of unknown etiology that healed spontaneously without disease relapse in six years. The patient’s spontaneous healing (drop of eosinophils in peripheral blood, followed by increased level of CA 125 in serum) affected the diagnosis accuracy.
Databáze: OpenAIRE
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