Evaluation of experimental subarachnoid analgesia with a combination of detomidine and ropivacaine for fl ank analgesia in cows

Autor: Ozgur Aksoy, Isa Ozaydin, Ali H. Kirmizigul, Engin Kilic, Savas Ozturk, Basak Kurt, Sadık Yayla, Mahmut Sozmen, Emine Atakisi
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Veterinarski arhiv
Volume 82
Issue 5
ISSN: 1331-8055
0372-5480
Popis: The aim of this study was to evaluate the analgesic efficacy of subarachnoid application of a low dose of detomidine combined with a low-dose of ropivacaine for flank analgesia in cows. Fifteen non pregnant adult cows of the Swiss Brown breed, weighing an average of 350 kg, were used. After applying local anaesthesia to the subcutaneous tissues in the area where the catheter was to be administered, a Tuohy needle was inserted into the subarachnoid space at the T13-L1 or L1-L2 region and a combination of detomidine (0.015 mg/kg)- ropivacaine (0.02 mg/kg) HCl was administered at a speed of 0.5 mL/min with a spinal catheter. Flank analgesia started within 1 min after the anaesthetic combinations was injected, the effective duration of the anaesthesia was 104 min on average and the anaesthesia had spread to the T12 and the L5 level. No statistically significant difference was found with regard to cardiopulmonary, haematological or haemodynamic parameters as measured before and during anaesthesia. A relatively small amount of detomidine HCl and ropivacaine HCl is sufficient to achieve safe and rapid analgesia in the left flank.
Cilj ovoga istraživanja bio je procijeniti učinkovitost analgezije u slabinskom području u krava nakon subarahnoidalne primjene male doze detomidina u kombinaciji s malom dozom ropivakaina. U istraživanju je korišteno 15 negravidnih krava Brown Swiss pasmine, s prosječnom tjelesnom masom od 350 kg. Nakon lokalne anestezije potkožnih tkiva u području oko katetera, uz pomoć Tuohy-eve igle u subarahnoidalni prostor T13-L1 ili L1-L2 primijenjena je kombinacija detomidina (0,015 mg/kg) i ropivakaina (0,02 mg/kg) HCl, u količini od 0,5 mL/min. Analgezija slabinskog područja započela je unutar jedne minute nakon primjene anestetika, a trajanje anestezije prosječno je iznosilo 104 min uz širenje do razine T12 i L5. Vrijednosti srčanoplućnih, hematoloških i hemodinamskih pokazatelja nisu se statistički značajno razlikovale prije i tijekom anestezije. Relativno mala količina detomidina HCl i ropivakaina HCl dostatna je za postizanje sigurne i brze analgezije lijevoga slabinskog područja.
Databáze: OpenAIRE
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