White Blood Cell Count in Different Stages of Chronic Periodontitis
| Autor: | Ana Pejčić, Ljiljana Kesić, Zoran Pešić, Dimitrije Mirković, Mariola Stojanović |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Acta clinica Croatica Volume 50 Issue 2 |
| ISSN: | 1333-9451 0353-9466 |
| Popis: | Periodontal disease is considered to be an inflammatory disorder that is related to the accumulation of oral microbial biofilm and the host response to this accumulation. The host reaction to gingival microorganisms is characterized in part by increase in the polymorphonuclear leukocyte counts, which is one of the most important steps in host defense. Exaggerated leukocytes and neutrophils of host response are a very important component in the pathogenesis of periodontal disease. The purpose of this study was to investigate the relationship between white blood cell count and periodontal disease in subjects with moderate and severe periodontitis and in control subjects with healthy periodontal tissues. Leukocytes for the present study were obtained from peripheral venous blood of 50 patients with moderate periodontitis, 50 patients with severe periodontitis and 25 healthy subjects. The clinical parameters of periodontitis including plaque index, bleeding on probing and gingival index were determined in all study subjects. In both moderate and severe periodontitis, the results indicated a significantly higher count of neutrophils (p Parodontna bolest je upalni poremećaj koji je povezan s akumulacijom oralnog mikrobnog biofilma i odgovorom domaćina na tu akumulaciju. Reakciju domaćina na gingivne mikroorganizme karakterizira donekle i povećanje broja polimorfonuklearnih leukocita, koji je jedan od najvažnijih koraka u odgovoru domaćina. Povećanje leukocita i neutrofila u okviru odgovora domaćina je veoma važna komponenta u patogenezi parodontne bolesti. Cilj ovoga istraživanja bio je ispitati vezu između broja bijelih krvnih zrnaca i parodontne bolesti kod ispitanika s blagom i uznapredovalom parodontopatijom i kontrolnih ispitanika sa zdravim parodontnim tkivom. Uzorak krvi za ispitivanje broja leukocita u ovom se istraživanju uzimao iz periferne venske krvi 50 ispitanika s umjerenom, 50 ispitanika s uznapredovalom parodontopatijom i 25 kontrolnih ispitanika. Klinički parametri parodontopatije, tj. plak indeks, indeks krvarenja i gingivni indeks određivali su se kod svih ispitanika. Kod obje skupine s parodontopatijom rezultati su pokazali značajno povećan broj neutrofila (p |
| Databáze: | OpenAIRE |
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