Hepatitis E Virus Infections in Horses, Dogs and Cats in the Republic of Croatia
| Autor: | Rogić, Lucija, Stevanović, Vladimir, Benvin, Iva, Jeličić, Pavle, Barbić, Ljubo |
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| Jazyk: | chorvatština |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Veterinar Volume 59. Issue 2. |
| ISSN: | 0303-5409 |
| Popis: | Hepatitis E je emergentna zoonoza sa sve većom javnozdravstvenom važnošću u svijetu. U posljednjem je desetljeću ustanovljena u ljudi na području Republike Hrvatske (RH), a visoka seroprevalencija dokazana je u divljih i domaćih svinja. U RH su istraživane i mogućnosti infekcija drugih vrsta životinja, među kojima je virus dokazan u žutogrlom mišu, dok su druge istraživane vrste bile negativne. Konji, psi i mačke dosad nisu pretraživani te je cilj ovog istraživanja bio po prvi put istražiti prisutnost i seroprevalenciju infekcije virusom hepatitisa E u konja i kućnih ljubimaca u RH. U tu svrhu ukupno su pretražena 264 uzorka seruma konja, 308 uzoraka seruma pasa te 88 uzoraka seruma mačaka primjenom indirektnog imunoenzimnog testa. Svi su pretraženi uzorci seruma konja i mačaka bili negativni, dok je infekcija virusom hepatitisa E potvrđena u jednog psa, tako da je seroprevalencija u pasa 0,3 %. Negativni rezultati u konja dokazuju nisku proširenost uzročnika u okolišu, a negativni rezultati u mačaka, kao i niska seroprevalencija u pasa da su kućni ljubimci u urbanim sredinama zanemarivo izloženi virusu hepatitisa E te stoga ni nemaju važnu ulogu u javnom zdravstvu. S druge strane, u serološki pozitivnog psa kliničko očitovanje i laboratorijski nalazi odgovarali su onima u ljudi oboljelih od hepatitisa E. Stoga je u kliničkoj praksi u slučaju hepatitisa u pasa potrebno isključiti i ovog emergentnog zoonotskog uzročnika radi razjašnjavanja kliničke važnosti infekcija HEV-a u pasa kao i potencijalnog rizika za javno zdravstvo. Hepatitis E is an emerging zoonosis and of growing public health importance worldwide. In the last decade, it has been established itself in humans in the territory of the Republic of Croatia (RH), and a high seroprevalence has been proven in wild boars and pigs. In the Republic of Croatia, the possibilities of infection of other animal species were also investigated. The virus was detected in yellow-throated mice, while the other species studied were negative. Horses, dogs and cats have not been investigated so far, and the aim of this study was to investigate for the first time the presence and seroprevalence of hepatitis E virus infection in horses and pets in the Republic of Croatia. For this purpose, a total of 264 horse serum samples, 308 dog serum samples and 88 cat serum samples were tested using an indirect enzyme-linked immunosorbent assay. All the tested serum samples from horses and cats were negative, while hepatitis E virus infection was confirmed in one dog so that the seroprevalence in dogs was 0.3%. The negative results in horses indicate the low prevalence of the pathogen in the environment, and the negative results in cats, as well as the low seroprevalence in dogs, indicate that pets in urban areas have negligible exposure to the hepatitis E virus and consequently do not play a significant role in public health. On the other hand, in serologically positive dogs, the clinical manifestations and laboratory findings corresponded to those in people with hepatitis E. Therefore, in clinical practice, in cases of hepatitis in dogs, it is necessary to exclude this emerging zoonotic pathogen to monitor the clinical significance of HEV infections in dogs and the potential risk to public health. |
| Databáze: | OpenAIRE |
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