Undifferentiated Carcinoma of the Epididymis
| Autor: | Aydin Aydin, Hamit Zafer Aksoy, Abdulkadir Reis, Feyyaz Özdemir |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Acta clinica Croatica Volume 50 Issue 3 |
| ISSN: | 1333-9451 0353-9466 |
| Popis: | Epididymal tumors are uncommon and usually benign, with only 25% of them being malignant. Undifferentiated epididymal carcinoma in particular is extremely rare. We report on a 54-year-old male patient presented with right testicular pain and scrotal mass for the last 6 months. Laboratory investigations were unremarkable but epididymal biopsy result was epididymal undifferentiated carcinoma. Inguinal radical orchidectomy was performed and pathological examination of the surgical specimen confirmed the presence of undifferentiated carcinoma. Then, adjuvant chemoradiotherapy (four cycles of cisplatin-etoposide chemotherapy and radiotherapy) was administered. After four months, lung metastases were detected and three doses ifosfamide-Adriamycin chemotherapy were given, but the patient died due to the disease progression. Reports of epididymal undifferentiated carcinoma are extremely rare and the present report emphasizes the need of including epididymal undifferentiated carcinoma in the differential diagnosis of an epididymal mass. Tumori epididimisa su rijetki i najčešće dobroćudni te ih je samo 25% zloćudno. Nediferencirani karcinom epididimisa iznimno je rijedak. Opisuje se slučaj 54-godišnjeg muškarca koji je primljen zbog bolova u desnom testisu i tvorbe u skrotumu u posljednjih šest mjeseci. Laboratorijski nalazi bili su normalni, ali je biopsija epididimisa ukazala na nediferencirani karcinom epididimisa. Napravljena je radikalna ingvinalna orhidektomija, a patološko ispitivanje kirurškog uzorka potvrdilo je prisutnost nediferenciranog karcinoma. Tada je bolesniku propisana dodatna kemoradioterapija (četiri ciklusa kemoterapije cisplatin-etoposid i radioterapija). Nakon četiri mjeseca otkrivene su metastaze u plućima, pa je bolesnik primio tri doze kemoterapije ifosfamid-adriamicin, ali je nastupila smrt zbog progresije bolesti. Izvješća o nediferenciranom karcinomu epididimisa iznimno su rijetka, stoga se ovim prikazom slučaja ukazuje na potrebu uključivanja nediferenciranog karcinoma epididimisa u diferencijalnu dijagnostiku novotvorina epididimisa. |
| Databáze: | OpenAIRE |
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