Rare breast tumors
| Autor: | Ilija Guteša, Andrej Roth, Ivan Milas, Danko Velimir Vrdoljak, Zvonimir Zore, Mirko Gulan, Mladen Stanec |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Libri Oncologici : Croatian Journal of Oncology Volume 42 Issue 1-3 |
| ISSN: | 2584-3826 0300-8142 |
| Popis: | Invasive breast cancer is a heterogeneous disease which occurs with diff erent clinical presentations, pathohistological characteristics and clinical course. Most common types are invasive ductal carcinoma not otherwise specified (IDC-NOS, 70-80%) and invasive lobular carcinoma (5 – 15%). Systemic therapy of breast carcinomas is mostly determined by their molecular classification, which is based on genetic research of NOS ductal breast cancer, without the inclusion of rare histological types. Since some rare breast tumors have excellent prognosis despite unfavorable molecular characteristics, when deciding on the optimal treatment, both molecular and prognostic characteristics should be considered. Tumors of non-epithelial origin, such as sarcomas, lymphomas and phyllodes tumors also appear in breasts. Karcinom dojke je heterogena bolest s raznolikom kliničkom slikom, patohistološkim karakteristikama i kliničkim tijekom. Najčešći tipovi karcinoma dojke su invazivni duktalni karcinom (IDC-NOS, 70-80 %) i invazivni lobularni karcinom (5-15%). Sustavno liječenje karcinoma dojke temelji se na molekularnoj klasifikaciji, koja je osnovana na genetskim istraživanjima NOS karcinoma, bez uključivanja rijetkih karcinoma dojke. Kako su neki rijetki tumori unatoč nepovoljnim molekularnim karakteristikama vrlo dobre prognoze, pri odlučivanju o načinu liječenja rijetkih tumora dojki, osim molekularnih, potrebno je uzeti u obzir i prognostičke karakteristike tih tumora. U dojkama se pojavljuju i tumori neepitelnog porijekla, poput sarkoma, limfoma i phyllodes tumora. |
| Databáze: | OpenAIRE |
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