Hereditary Protein S Deficiency and Recurrent Venous Thrombosis: A Case Report
| Autor: | Petar Gaćina, Dubravka Čaržavec, Biserka Raić, Boris Car, Vladimir Stančić, Vlatko Pejša |
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| Jazyk: | angličtina |
| Rok vydání: | 2004 |
| Předmět: | |
| Zdroj: | Acta clinica Croatica Volume 43 Issue 3 |
| ISSN: | 1333-9451 0353-9466 |
| Popis: | A case is presented of a 32-year-old female with hereditary protein S deficiency associated with pulmonary embolism and recurrent deep venous thrombosis of lower extremities. Other proteins known to be associated with familial thromboembolic disease, including antithrombin, plasminogen, fibrinogen, protein C, factor V Leiden and prothrombin G20210A, were normal. Her mother, grandmother and great-grandfather had a history of thromboembolic disease. This report illustrates the importance of protein S measurement in patients suspected of having inherited venous thrombotic disorders. Prikazan je slučaj 32-godišnje bolesnice s nasljednim nedostatkom proteina S povezanim s plućnom embolijom i opetovanom dubokom venskom trombozom donjih ekstremiteta. Ostali čimbenici nasljedne trombofilije, tj. antitrombin, plazminogen, fibrinogen, protein C, faktor V. Leiden i protrombin G20210A su bili uredni. Obiteljska anamneza majke, bake i pradjeda ukazivala je na opetovanu vensku trombozu i plućnu emboliju. Navodi se značenje određivanja proteina S u bolesnika sa sumnjom na nasljednu trombofiliju. |
| Databáze: | OpenAIRE |
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