Odlaganje homogentizinske kiseline u duge kosti s litičkim promjenama dijafiza u bolesnice s ohronozom

Autor:	Zrinka Jajić, Ivo Jajić, Tomislav Nemčić
Jazyk:	angličtina
Rok vydání:	2000
Předmět:	musculoskeletal diseases sense organs Ochronosis Ochronosis - pathology Ochronosis - complications Homogentisic acid Ohronoza Ohronoza patologija Ohronoza komplikacije Homogentizinska kiselina musculoskeletal system
Zdroj:	Acta clinica Croatica Volume 39 Issue 2
ISSN:	1333-9451 0353-9466
Popis:	Presentation is made of a 58-year-old female patient with alkaptonuria and ochronosis. Calcification and ossification of intervertebral disks in the lumbar, thoracic and cervical spine were developed. In addition, diaphyseal lytic changes of the femur, tibia and fibula were observed. The lesions were diffuse and unequal. Diaphysis of the long bones had a ‘moth-eaten’ bone appearance. No data on such changes were found in the available literature. Prikazana je 58-godišnja bolesnica s alkaptonurijom i ohronozom. Nađena je kalcifikacija i osifikacija intervertebralnog diskalumbalne, torakalne i vratne kralješnice. Usto, bile su razvijene litičke promjene femura, tibije i fibule. Lezije su bile difuzne. Dijafize dugih cjevastih kostiju izgledale su kao da su ih ‘izjeli moljci’. U dostupnoj literaturi nije nađen opis takvih promjena.
Databáze:	OpenAIRE
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