Atypical glandular cells in pap smear as a primarily presentation of ovarian serous borderline tumor
| Autor: | Jurič, Danijela, Barišić, Ana, Rajhvajn, Sanda, Mahovlić, Vesna, Petrović, Davor, Macan, Marija, Grgić, Franjo |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Libri Oncologici : Croatian Journal of Oncology Volume 49 Issue 2-3 |
| ISSN: | 2584-3826 0300-8142 |
| Popis: | The Pap test is designed as a screening test to detect primarily carcinoma of the cervix and its precursors, most often of squamous type. Rarely atypical or malignant cells found in cervical smear can be indication for the existence of an extrauterine disease. We present a case of a 26 year old woman with very small asymptomatic ovarian bilateral borderline tumors whose diagnosis was triggered by finding of atypical glandular cells with psammoma bodies on Pap smear. She had a history of abnormal Pap smears and was admitted to our Hospital for colposcopy. Pap smear was taken and reported as atypical glandular cells (AGC) with psammoma bodies. Colposcopically directed biopsy along with an endocervical curettage showed no abnormalities as well as transvaginal ultrasound examination. Three months later control Pap smear confirmed AGC with psammoma bodies (suggestive of endometrial or serous origin), ultrasound showed the presence of indistinctive, hyperechoic mass 2 cm in diameter in the left ovary along with slightly elevated CA-125 and diagnostic hysteroscopy and laparoscopy was performed. At laparascopy, both ovaries had surface cauliflower like papillary projections measuring up to 3 cm. A histological examination revealed bilateral serous borderline tumor. Papa test je test probira primarno namijenjen za rano otkrivanje karcinoma cerviksa i njegovih prekursora, najčešće pločastog tipa. Rijetko nalaz atipičnih ili malignih stanica u Papa testu može biti prvi znak tumora ekstrauterinog porijekla. U ovom radu prikazujemo slučaj 26 godišnje pacijentice s vrlo malim asimptomatskim bilateralnim borderline tumorima jajnika čija je dijagnoza pokrenuta nalazom atipičnih žljezdanih stanica sa psamomskim tjelešcima u Papa testu. Pacijentica je upućena u našu bolnicu na kolposkopiju radi abnormalnih nalaza Papa testa. Kod nas uzeti Papa test pokazao je atipične glandularne stanice (AGC) sa psamomskim tjelešcima. Kolposkopski vođena biopsija i endocervikalni ekskohleat nisu pokazali abnormalnosti, kao ni transvaginalni ultrazvučni pregled. Tri mjeseca kasnije ponovljeni Papa test potvrđuje AGC sa psamomskim tjelešcima (porijeklo endometralno ili serozno), ultrazvučni nalaz opisuje uz lijevi jajnik nejasnu hiperehogenu tvorbu promjera 2 cm, uz blago povišeni CA 125 zbog čega je učinjena dijagnostička histeroskopija i laparoskopija. Na operaciji su nađeni jajnici obostrano s tumorskim tvorbama karfiolastog izgleda veličine do 3 cm. Patohistološki je potvrđen serozni borderline tumor oba jajnika. |
| Databáze: | OpenAIRE |
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