Concurrent Deep Vein Thrombosis and Pulmonary Embolism Associated with Hyperthyroidism: a Case Report
| Autor: | Katić, Josip, Katić, Ana, Katić, Karla, Duplančić, Darko, Lozo, Mislav |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Acta clinica Croatica Volume 60. Issue 2. |
| ISSN: | 1333-9451 0353-9466 |
| Popis: | Numerous disorders of coagulation and fibrinolysis have been reported in patients with thyroid diseases, especially with hyperthyroidism. Most articles are focused on deep vein thrombosis risk, however, few of them describe association between hyperthyroidism and pulmonary embolism. We report a case of a 43-year-old woman with long-term uncontrolled hyperthyroidism complicated by venous thromboembolism. The potential mechanisms could be endothelial dysfunction, decreased fibrinolytic activity, and increased levels of coagulation factors. Thyroid evaluation should be recommended in patients with unprovoked venous thromboembolic events. Različiti poremećaji koagulacije ponekad se povezuju s bolestima štitnjače, najčešće hipertireozom. Većina dosadašnjih radova je usredotočena na rizik duboke venske tromboze kod takvih bolesnika, dok je u vrlo malom broju radova opisana povezanost hipertireoze i plućne embolije. Prikazuje se slučaj 43-godišnje bolesnice s dugogodišnjom nekontroliranom hipertireozom i posljedičnim akutnim venskim tromboembolizmom. Vjerojatni patofiziološki mehanizam uključuje oštećenje endotela, smanjenje fibrinolitičke aktivnosti i povećanu razinu faktora koagulacije. Klinička i laboratorijska evaluacija štitnjače preporučljiva je u bolesnika s neprovociranim tromboembolijskim događajem. |
| Databáze: | OpenAIRE |
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