MIJELOLIPOMI NADBUBREŽNE ŽLIJEZDE - PRIKAZ SERIJE OD 15 BOLESNIKA

Autor: MIRAN BEZJAK, PATRICIJA SESAR, MONIKA ULAMEC, IVANA PAVIĆ, AUGUST MIJIĆ, BORISLAV SPAJIĆ, BOŽO KRUŠLIN
Jazyk: chorvatština
Rok vydání: 2013
Předmět:
Zdroj: Acta medica Croatica : Časopis Akademije medicinskih znanosti Hrvatske
Volume 67
Issue 3
ISSN: 1848-8897
1330-0164
Popis: Mijelolipom je rijedak, dobroćudan, nefunkcionalni tumor, najčešće smješten u kori nadbubrežne žlijezde. Sastoji se od zrelog masnog tkiva s komponentama hematopoetskog tkiva u različitom omjeru. Postoje stanovite nedoumice vezane uz dijagnosti¬ciranje i liječenje mijelolipoma pa je zbog toga važno sagledati sve aspekte te lezije i okolnosti u kojima se ona pojavljuje. Ovdje prikazujemo seriju od 15 bolesnika s mijelolipomom dijagnosticiranih na Zavodu za patologiju “Ljudevit Jurak” KBC-a “Sestre milosrdnice”. Od 15 bolesnika desetorica su bili muškarci (jedan s bilateralnim tumorom) u dobi od 4 do 73 godine te pet žena u dobi od 51 do 54 godine. Makroskopski, tvorbe su bile ovalne, inkapsulirane, žućkaste, mekane mase smještene u nadbubrež¬nim žlijezdama. Promjer tumora kretao se od 0,5 do 13,9 cm. Mikroskopski su bili građeni od umnoženih zrelih masnih stanica u kombinaciji s mijeloidnim tkivom koje se pretežno sastojalo od megakariocita, eritroidnih stanica i limfocita. Nije bilo znakova atipije. Bolesnici su nakon kirurškog zahvata dobro i bez recidiva.
Myelolipoma is a rare, benign, non-functioning tumor most frequently located in the adrenal cortex. It consists of mature fatty tissue with components of hematopoietic tissue in different proportions. There are certain ambiguities related to the diagnosis and therapy of myelolipoma, and it is therefore important to keep in view all the aspects of the lesion and the circumstances in which it develops. This paper presents a series of 15 patients with myelolipoma diagnosed at the Ljudevit Jurak Department of Pathology, Sestre milosrdnice University Hospital Center. Out of 15 patients, 10 were men (one of them with bilateral tumor) aged 41 to 73, and 5 were women aged 51 to 54. Macroscopically, the tumors were oval, encapsulated, yellowish, soft masses located in the adrenal glands. The diameter of the tumors ranged between 0.5 and 13.9 cm. Microscopically, they consisted of multiplied mature adipose cells combined with myeloid tissue composed largely of megakaryocytes, erythroid cells and lymphocytes. In all patients, the postoperative course was uneventful with no recurrences.
Databáze: OpenAIRE
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