Severe bovine papillomatosis: detection of bovine papillomavirus in tumour tissue and efficacy of treatment using autogenous vaccine and parammunity inducer
| Autor: | Nenad Turk, Željko Župančić, Vilim Starešina, Snježana Kovač, Tomislav Babić, Mario Kreszinger, Stipica Ćurić, Ljubo Barbić, Zoran Milas |
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| Jazyk: | angličtina |
| Rok vydání: | 2005 |
| Předmět: | |
| Zdroj: | Veterinarski arhiv Volume 75 Issue 5 |
| ISSN: | 1331-8055 0372-5480 |
| Popis: | Two cases of severe bovine papillomatosis occurred in northwest Croatia during 2000 are described. Diagnosis was based on presented clinical signs, histopathological findings, and detection of the papillomavirus by transmission electron microscopy. Animals successfully recovered following treatment with the autogenous (non-purified) vaccine and a parammunity inducer. For the first time in Croatia we report the detection of papillomavirus by electron microscopy. U radu su opisana dva slučaja generalizirane papilomatoze u goveda ustanovljena u sjeveroistočnom području Republike Hrvatske tijekom 2000. godine. U oba slučaja dijagnoza je postavljena na osnovi kliničke slike, histopatološke pretrage tumorskog tkiva i nalaza papilomavirusa goveda u homogenizatu tumorskog tkiva elektronskom mikroskopijom. Životinje su liječene autogenom vakcinom i imunomodulatorom (Baypamun®, Bayer Pharma, Leverkusen, Germany), a tumorozne promjene u potpunosti su iščezle nakon 6 tjedana od početka liječenja. U radu je po prvi put u Republici Hrvatskoj opisan nalaz papilomavirusa goveda u tumorskom tkivu elektronskom mikroskopijom. |
| Databáze: | OpenAIRE |
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