Promjene na sluznici usne šupljine kod bolesnika s lihen planusom
| Autor: | Sanja Peršić, Liborija Lugović Mihić, Jozo Budimir, Mirna Šitum, Vedrana Bulat, Iva Krolo |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
stomatognathic diseases
integumentary system stomatognathic system Lichen Planus Mouth Mucosa - pathology Lichen Planus Oral - diagnosis Lichen Planus Oral - pathology Lichen Planus Oral - complications Lichen planus Sluznica usne šupljine - patologija Lichen planus oralni - dijagnostika Lichen planus oralni - patologija Lichen planus oralni - komplikacije skin and connective tissue diseases |
| Zdroj: | Acta clinica Croatica Volume 47 Issue 2 |
| ISSN: | 1333-9451 0353-9466 |
| Popis: | Forty patients with lichen planus admitted to University Department of Dermatology and Venereology, Sestre milosrdnice University Hospital in Zagreb during the 2004-2006 period were assigned to this retrospective study. In these 40 patients (27 female and 13 male), lichen planus was diagnosed on the basis of clinical presentation, laboratory findings and histopathologic analysis. The results obtained indicated an increased prevalence of lichen planus in middle-aged patients (40% of patients were aged 40-60), with a significant female predominance (67.5% vs. 32.5%). The majority of patients with lichen planus presented with both cutaneous and oral lesions (62.5%), one third of cases had only cutaneous lesions (35%), and only one patient had isolated oral lesions (2.5%). The initial symptoms in patients with lichen planus usually manifested on the skin (82.5%), in oral cavity (5%), or both simultaneously. Oral lesions usually developed on buccal mucosa (88.5%) in the form of Wickham.s striae. All patients were administered topical therapy (corticosteroids, keratolytics), while 55% of patients were given both systemic and topical therapy (corticosteroids, retinoids). Phototherapy was used in 27.5% of patients. The management of patients with oral lichen planus lesions requires multidisciplinary approach including dermatologists and oral pathologists, general practitioners, as well as ENT specialists, internal medicine specialists, and others. Ovo retrospektivno istraživanje obuhvatilo je bolesnike hospitalizirane zbog lihen planusa u Klinici za dermatovenerologiju KB "Sestre milosrdnice" u Zagrebu u razdoblju od siječnja 2004. do kraja 2006. godine. Obuhvaćeno je 40 bolesnika (27 žena i 13 muškaraca) koji su bolovali od lihen planusa, a dijagnoza je postavljena na temelju kliničko-laboratorijskih pretraga te patohistološkog nalaza. Prema našim rezultatima lihen se najčešće javljao u dobi od 40. do 60. godine (45%), češće kod žena (67,5%) nego kod muškaraca (32,5%). Većina bolesnika je istodobno imala promjene na koži i sluznici (62,5%), kod oko trećine bolesnika promjene su bile isključivo na koži (35%), dok je samo jedan bolesnik imao promjene isključivo na sluznici usne šupljine (2,5%). Bolest je najčešće započinjala na koži (82,5%), zatim na sluznici usne šupljine (5%), dok je istodobni početak pojave promjena na sluznici usne šupljine i koži zabilježen u 12,5% bolesnika. Promjene usne šupljine najčešće su bile lokalizirane na bukalnoj sluznici (88,5%), uglavnom u obliku Wickhamovih strija (65,4%). Kod svih bolesnika se primijenila lokalna terapija (kortikosteroidi, keratolitici), dok je 55% bolesnika uz lokalnu primilo i sistemsku terapiju (kortikosteroidi, retinoidi). Kod 27,5% bolesnika je provedena fototerapija. S obzirom na to da se promjene kod lihen planusa često javljaju na sluznici usne šupljine potreban je multidisciplinski pristup koji uključuje suradnju specijalista dermatovenerologa, oralnog patologa, liječnika obiteljske medicine, ORL, internista i drugih. |
| Databáze: | OpenAIRE |
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