Hemovigilancija i poslijetransfuzijske reakcije na krvne sastojke u bolesnika sa solidnim tumorima

Autor: Banović, Miroslav, Lovrić, Marija, Veliki-Dalić, Irena, Banović, Miro
Jazyk: angličtina
Rok vydání: 2009
Předmět:
Zdroj: Libri Oncologici : Croatian Journal of Oncology
Volume 37
Issue 1-3
ISSN: 2584-3826
0300-8142
Popis: Hemovigilance is a system of surveillance and alarm in transfusion activities from blood donor selection to the followup of the blood component recipients, gathering and analyzing all untoward effects of blood transfusion in order to correct their cause and prevent recurrence. A 5-year surveillance (2005-2009) showed the overall consumption of 6790 unit doses (1358/year): erythroconcentrate (EC) 973.4 ± 71, platelet concentrate (PC) 216 ± 66.93, fresh frozen plasma (FFP)122.4 ± 59.05 and cryoprecipitate (CP) 46.2 ± 26.63. During the five years, there were 38 adverse events (22 non-hemolytic febrile transfusion reactions (NHFTR), 16 allergic reactions (AR), or an average annual rate of 7.6 reactions ( 4.4 NHFTR, 3.2 AR). Neither serious adverse events nor death was reported. EC caused 0.043% of NHFTR (risk 1:2,326) and 0.015% of AR (risk 1:3,125), while FFP lead to 0.18% of NHFTR (risk 1:556) and 1.18% of AR (risk 1:85). No reaction to PC and CP was reported. The annual rate for 10,119 blood components (EC,PC, FFP,CP) was 0.043% of NHFTR (risk 1:2,326), and 0.032% of AR (risk 1:3,125). Our results are within the range of worldwide standards.
Hemovigilancija je sustav nadzora i alarma u transfuzijskoj medicini. Prati tijek krvi i krvnih pripravaka davatelja do krajnjeg potrošača. Prikuplja i analizira neželjene doga|aje kako bi ih bilo manje u budućnosti. Potrošnja doza praćena je 5 godina (2005-2009) i bila je 6790 (1358/god): eritrokoncentrata (EK) 973;4 ± 71; trombokoncentrata (TK) 216 ± 66;93; svježe smrznute plazme (SSP)122;4 ± 59;05 i krioprecipitata (KP) 46;2 ± 26;63. Tijekom 5 godina bilo je 38 neželjenih reakcija (22 nehemolitičnih febrilnih transfuzhijskih reakcija NHFTR; 16 alergijskih reakcija AR). Prosječno godišnje 7;6 reakcija (4;4 NHFTR; 3;2 AR). Nije bilo težih reakcija i smrti. EK su izazvali 0;043% NHFTR (rizik 1:2326) i 0;015% AR (rizik 1:3125); a SSP 0;18% NHFTR (rizik 1:556) i 1;18% AR (rizik 1:85).Reakcija na TK i KP nije bilo. Na 10119 pripravaka (EK;TK;SSP;KP) godišnje bilo je 0;043% NHFTR (rizik 1:2326); te 0;032% AR (rizik 1:3125). Naši rezultati su u rangu svjetskih standarda.
Databáze: OpenAIRE
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