Emergence of Uropathogenic Extended-Spectrum b Lactamases-Producing Escherichia coli Strains in the Community
| Autor: | Tatjana Marijan, Jasmina Vraneš, Branka Bedenić, Ana Mlinarić-Džepina, Vanda Plečko, Smilja Kalenić |
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| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: | |
| Zdroj: | Collegium antropologicum Volume 31 Issue 1 |
| ISSN: | 1848-9486 0350-6134 |
| Popis: | The aim of this study was to determine the virulence characteristics and resistance pattern of the extended-spectrum b lactamases (ESBLs)-producing Escherichia coli strains isolated from urine of outpatients in the Zagreb region during a five-month period, and to compare them with the non ESBLs-producing E. coli strains isolated in the same period. Out of 2,451 E. coli strains isolated from urine of nonhospitalized patients with significant bacteriuria, a total of 39 ESBLsproducing strains (1.59%) were detected by a double-disk diffusion technique and by the broth-dilution minimal inhibitory concentration reduction method. The 45 non ESBLs-producing strains were randomly chosen, and phenotype of the two groups of strains was characterized and compared. Serogroup O4, hemolysin production, expression of P- and type 1 fimbriae as well as resistance to gentamicin and amikacin were significantly more prevalent characteristics among the ESBLs-producing strains than among non ESBLs-producing strains (p0.05). Chromosomal DNA analysis by pulsed-field gel electrophoresis exhibited a great genomic similarity among ESBLs-producing strains and revealed that those highly virulent and resistant E. coli strains isolated from urine of outpatients in the Zagreb region had a clonal propagation. |
| Databáze: | OpenAIRE |
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