Nitric Oxide Synthesis Inhibition and Anti-Inflammatory Effect of Polypeptide Isolated from Chicken Feather Meal in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages

Autor:	Aurachorn Inkanuwat, Romteera Sukaboon, Onrapak Reamtong, Pravit Asawanonda, Ake Pattaratanakun, Tanatorn Saisavoey, Papassara Sangtanoo, Aphichart Karnchanatat
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	dušikov oksid protuupalni učinak brašno od perja hidrolizat proteina polipeptid makrofag RAW 264.7 nitric oxide anti-inflammatory activity chicken feather meal protein hydrolysate polypeptide macrophage RAW 264.7
Zdroj:	Food Technology and Biotechnology Volume 57 Issue 2
ISSN:	1334-2606 1330-9862
Popis:	Dušikov oksid ima ključnu ulogu u mehanizmu nastanka upalnog procesa te uzrokuje ozljedu tkiva. Brašno od perja kokoši bogato je aminokiselinama te može poslužiti za inhibiciju sinteze dušikovog oksida kao hidrolizat peptida. Pripremljeni su hidrolizati brašna od perja s protuupalnim svojstvima, koji su razdvojeni u pet skupina prema molekulskoj masi. Najmanja je frakcija ( Nitric oxide (NO) plays a key role in the pathogenesis of inflammation and has been implicated in endotoxin-induced tissue injury. Chicken feather meal is a rich source of amino acids that may serve as a peptide hydrolysate to inhibit NO activity. Anti-inflammatory hydrolysates of chicken feather meal were prepared and fractionated into five samples based on molecular mass. The smallest fraction (
Databáze:	OpenAIRE
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