Evaluation of the diagnostic value of static brain chintigraphy in detection of brain tumors
| Autor: | Ivan Mihaljević, Aleksandar Rusić, Nedeljko Topuzović, Đuro Vranković, Krešimir Glavina, Branislav Krstonošić |
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| Jazyk: | angličtina |
| Rok vydání: | 1991 |
| Předmět: | |
| Zdroj: | Medicinski vjesnik Volume 23 Issue (1-2) |
| ISSN: | 0350-6487 |
| Popis: | U radu se daje usporedna nuklearno-neurološka, neuroradiološka i oftalmološka studija 55 bolesnika s tumorima mozga, čija je dijagnoza patohistološki potvrđena. Procijenjena je dijagnostička vrijednost statičke scintigrafije mozga i njezina podudarnost s nalazima fundusa, elektroencefalografije, cerebralne angiografije i kompjutorizirane tomografije u otkrivanju moždanih tumora i njihovih recidiva. Preoperativna dijagnostička senzitivnost statičke scintigrafije mozga iznosi 92%, a nešto je niža za otkrivanje recidiva nakon učinjene kirurške ekstirpacije tumora (85%). Postoperativna je specifičnost pretrage za recidiv manja od njezine osjetljivosti (66%). Međutim, zahvaljujući različitom vezivanju radiofarmaka u moždanim lezijama, istaknuto je da statička scintigrafija mozga, osim anatomskopatoloških, može dati i patofiziološke diferencijalnodijagnostičke podatke o svojstvima tumorskog tkiva, značajne za planiranje kirurškog zahvata. Ova metoda, zbog svoje neinvazivnosti, mogućnosti ambulantnog izvođenja i malog radijacijskog opterećenja bolesnika, ostaje vrlo dobra screening metoda u otkrivanju moždanih tumora. In this study, nucleo-neurologic, neuro-radiologic and opthalmologic findings of 55 patients with pathohistologically verified diagnosis were analyzed. The diagnostic value of brain scinthigraphy and its complementarity with the findings of fundus examination, electroencephalography, cerebral angiography and computerized tomography in the detection of brain tumors and their postoperative recurrence were estimated. Preoperative diagnostic sensitivity of static brain scintigraphy was 92%, but it was somewhat lower in the detection of recurrence after surgical tumor removal (85%). The postoperative specificity of this procedure was lower than its sensitivity (66%). Yet, due to different binding of radiopharmacenticals within brain lesions, static brain scintigraphy could apart from anatomicopathologic data, provide important pathophysiologic differential diagnostic data on the tumor tissue, essential for determination of the surgical procedure. This method remains a very good brain screening technique, due to its non-invasiveness, possibility of ambulatory procedure and low patient iradiation. |
| Databáze: | OpenAIRE |
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