Tihi infarkt mozga
| Autor: | Lidija Tuškan-Mohar, Adriana Prunk Drmić, David Bonifačić, Igor Antončić, Olivio Perković, Siniša Dunatov |
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| Jazyk: | chorvatština |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Medicina Fluminensis : Medicina Fluminensis Volume 49 Issue 1 |
| ISSN: | 1848-820X 1847-6864 |
| Popis: | Akutni infarkt mozga svojim nastupom i simptomima uzrokuje relativno jasnu i prepoznatljivu kliničku sliku, no postoje kronične pojedinačne i/ili difuzne ishemične lezije mozga koje su klinički asimptomatske i duže vremena se ne prepoznaju. Termin tihi infarkt mozga često se koristi za opis infarkta mozga koji se slučajno utvrdi u osoba koje nikad ranije u svojoj povijesti bolesti nisu imale kliničke simptome tranzitorne ishemijske atake ili moždanog udara. Može ga se utvrditi obdukcijom ili neuroradiološkim pretragama, kompjutoriziranom tomografijom i magnetskom rezonancijom mozga. Radi se najčešće o malom infarktu u dubokim subkortikalnim regijama mozga i morfološki je sličan simptomatskom lakunarnom infarktu. Lakunarna ishemična lezija mozga posljedica je okluzije duboke, penetrantne arterije u čijoj se osnovi uglavnom nalazi hipertenzivna moždana mikroangiopatija. Tihom infarktu mozga posljednje se desetljeće pridaje velika pažnja jer su studije pokazale da prisutnost tihog infarkta mozga dvostruko povećava rizik nastanka simptomatskog moždanog udara i demencije. U ovom preglednom članku prikazujemo epidemiologiju, patofiziološka obilježja, čimbenike rizika i moguće posljedice tihog infarkta mozga. With its onset and symptoms the acute brain stroke causes relatively clear and recognizable clinical features. However, there are chronic, single and/or diffuse ischemic brain lesions which are clinically asymptomatic and which take longer to recognize. The term ”silent brain infarct” is frequently used to describe the brain infarct which is determined with the autopsy by chance or which could be determined with computerized tomography. Such brain infarct could also be determined using the brain magnetic resonance imaging on people who never before had clinical symptoms transient ischemic attack or brain stroke in their lives. For the most of the time this is about small infarct in deep sub-cortical brain regions. It is morphologically similar to symptomatic lacunar infarct. Lacunar ischemic brain lesion is the consequence of the deep, perforating artery occlusion. Its base is mainly the hypertensive brain microangiopathy. The silent brain infarct is given great attention in the last decade because the studies show the silent brain infarct presence doubles the symptomatic brain stroke and dementia risk. In this review we show the epidemiology, the pathophysiologic attributes, the risk factors and possible silent brain infarct consequences. |
| Databáze: | OpenAIRE |
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