MODIFICATION OF RYANODINE-SENSITIVE CALCIUM RELEASE CHANNELS GATING AND CALCIUM DYNAMICS IN CARDIOMYOCYTES BY TEMPERATURE IN ELECTRON-CONFORMATIONAL THEORY

Autor: Yaparov, B. Ya., Moskvin, A. S., Ryvkin, A. M.
Jazyk: ruština
Rok vydání: 2014
Popis: We took into account a temperature in an Electron-Conformational Model of SR-based Ca2+ Clock (ECM Clock). The results of modelling of ECM Clock show that higher temperature gives lower amplitude of cytosolic Ca2+ and higher frequency of oscillations and lower temperature destroys ECM Clock. Исследования поддержаны Программой повышения конкурентоспособности ведущих университетов РФ (постановление Правительства РФ № 211 от 16 марта 2013 г.).
Databáze: OpenAIRE