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Background T2DM is a metabolic disorder that is rapidly increasing in prevalence, it has become a 21st century epidemic and addressing this is one of the greatest global health challenges of our time. In the UK £10.3 billion or 10% of the NHS budget was spent on diabetes mellitus. It is essential that a prevention approach to T2DM is utilised within the NHS. Aims The aims of this study are to compare physiological, metabolic parameters and inflammatory markers from type 2 diabetes mellitus (T2DM) and non-diabetic (ND) volunteers over a 6-week exercise period. Methods This was a very interesting study where T2DM and ND volunteers completed one of three structured exercise programmes involving either a combination of cardio and resistance exercise, cardio exercise or resistance exercise twice a week for 6-weeks. Various parameters were recorded at baseline to compare with results after 1 exercise session and again after 12 exercise sessions. Key findings Oral glucose tolerance test area under the curve results showed noticeable reductions from 1612.40 to 1354.10 mmol/L*min. Weight reduced by 2.58 kg in the T2 combination group after intervention which showed a statistically significant reduction from before to after intervention with a p-value of 0.049. Time to peak reduced in the T2 resistance group from 80 to 47 minutes. Total cholesterol reduced in the T2 resistance group after intervention from 5.34 to 4.68 mmol/L. Inflammatory marker results are also presented at the end of the results chapter. |
