Influence of drugs and comorbidity on serum potassium in 15 000 consecutive hospital admissions

Autor: Henz, Samuel, Maeder, Micha T., Huber, Stephanie, Schmid, Michael, Loher, Marcel, Fehr, Thomas
Jazyk: angličtina
Rok vydání: 2017
Popis: Background. Drug trials often exclude subjects with relevant comorbidity or comedication. Nevertheless, after approval, these drugs will be prescribed to a much broader collective. Our goal was to quantify the impact of drugs and comorbidity on serum potassium in unselected patients admitted to the hospital. Methods. This was a retrospective pharmacoepidemiologic study in 15 000 consecutive patients admitted to the medical department of the Kantonsspital St. Gallen, a 700-bed tertiary hospital in eastern Switzerland. Patients with ‘haemolytic' plasma and patients on dialysis or with an estimated glomerular filtration rate (GFR)
Databáze: OpenAIRE