Fecal microbiota transplantation in recurrent Clostridium difficile infection in a patient with concomitant inflammatory bowel disease

Autor: Gravito-Soares, Marta, Gravito-Soares, Elisa, Portela, Francisco, Ferreira, Manuela, Sofia, Carlos
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Revista Española de Enfermedades Digestivas, Volume: 109, Issue: 6, Pages: 473-476, Published: JUN 2017
Popis: The use of fecal microbiota transplantation in recurrent Clostridium difficile infection and coexistent inflammatory bowel disease remains unclear. A 61-year-old man with ulcerative pancolitis was diagnosed with a third recurrence of Clostridium difficile infection, previously treated with metronidazole, vancomycin and fidaxomicin. Fecal microbiota transplantation of an unrelated healthy donor was performed by the lower route. After a twelve month follow-up, the patient remains asymptomatic without Clostridium difficile infection relapses or inflammatory bowel disease flare-ups. Fecal microbiota transplantation is relatively simple to perform, well-tolerated, safe and effective in recurrent Clostridium difficile infection with ulcerative pancolitis, as an alternative in case of antibiotic therapy failure.
Databáze: OpenAIRE