Ciprofibrate diminishes NON-HDLc and improves HDLc in patients with Frederickson type IV dyslipidemia phenotype

Autor: Bermúdez-Pirela, V, Souki, A, Cano-Ponce, C, Bermúdez-Arias, F, Mengual-Moreno, E, Leal-Gonzalez, E, Lemus-Antepaz, M, Cabrera de B, M, Amell de D, A, Leal de P, N, Cano-Peñaloza, R, Puche-Medina, G, Ramirez, I, Contreras, F, Velasco, M
Jazyk: angličtina
Rok vydání: 2005
Předmět:
Zdroj: Archivos Venezolanos de Farmacología y Terapéutica, Volume: 24, Issue: 2, Pages: 10-16, Published: 2005
Popis: Objective: Hypertriacylglyceridemia and low HDLc combination is one of the most common lipidic abnormalities. Thus, the aim of this study was to determine the effects of Ciprofibrate on patients with Frederickson’s Type IV dyslipidemia phenotype. Research design and methods: 75 patients with type IV dyslipidemia were assigned at random to one of two therapeutic options: Group A, AHA diet and physical activity and B, AHA diet, physical activity and Ciprofibrate 100 mg daily for 12 weeks. All patients underwent lipidic profile quantification before and after therapeutic intervention. Results: Ciprofibrate treatment group exhibited significantly reduction in total cholesterol (-14,2% vs. -4,8%; p
Databáze: OpenAIRE