| Autor: |
Araya Q, A. Verónica, Valera M, José M, Contreras B, Jorge, Csendes J, Attila, Díaz J, Juan C, Burdiles P, Patricio, Rojas C, Jorge, Maluenda G, Fernando, Smok S, Gladys, Poniachik T, Jaime |
| Jazyk: |
Spanish; Castilian |
| Rok vydání: |
2006 |
| Předmět: |
|
| Zdroj: |
Revista médica de Chile, Volume: 134, Issue: 9, Pages: 1092-1098, Published: SEP 2006 |
| Popis: |
Background: Non alcoholic fatty liver disease (NAFLD) is associated to diabetes mellitus, obesity, disturbances in serum lipid levels, insulin resistance and metabolic syndrome. Aim: To assess glucose tolerance and the presence of metabolic syndrome among patients with biopsy proven NAFLD. Patients and methods: Serum lipid levels, hepatic function tests were measured and an oral glucose tolerance test was performed in 46 patients (mean age 45±12 years, 36 females) without history of diabetes mellitus and with steatosis in a liver biopsy. Results: Mean body mass index of the sample was 37±12 kg/m². Seventeen percent had pure steatosis, 78% had steatohepatitis with or without fibrosis and 50% had fibrosis in the liver biopsy. Glucose intolerance and diabetes was found in 57% and 15% of cases, respectively. The presence of steatohepatitis was higher in diabetics, compared with subjects with glucose intolerance or a normal glucose response (43, 38 and 8%, respectively, p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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