Death-Associated Protein Kinase is Underexpressed in High-Grade Oral Squamous Cell Carcinoma
Autor: | Meneses, Ismário Silva de, Souza, Rafael Reis de, Jeraldo, Verónica de Lourdes Sierpe, Cavalcante, Danielle Rodrigues Ribeiro, Reis, Francisco Prado, Albuquerque Júnior, Ricardo Luiz Cavalcanti de |
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Jazyk: | angličtina |
Rok vydání: | 2010 |
Předmět: | |
Zdroj: | International Journal of Morphology, Volume: 28, Issue: 2, Pages: 609-613, Published: JUN 2010 |
Popis: | An immunohistochemical analysis of 40 cases of oral squamous cell carcinoma was performed to evaluate the relationship between the expression pattern of death-associated protein kinase (DAPk) positive cells with the histological malignancy grading of these lesions. According to our results, eleven cases (27.5%) were high-grade malignancy tumours and 29 (72.5%) were low-grade ones. We found that 92.86% of the low-grade tumours were positive to anti-DAP kinase antibody whereas only 7.14% of the high-grade tumours presented positivity, and this difference was statistically significant (p |
Databáze: | OpenAIRE |
Externí odkaz: |
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