Immunoexpression of Cell Proliferation Markers in Oral Squamous Cell Carcinoma

Autor: Pereira, Joabe dos Santos, Barroso, Keila Martha Amorim, Nonaka, Cassiano Francisco Weege, Pinto, Leão Pereira, de Souza, Lélia Batista
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: International journal of odontostomatology, Volume: 10, Issue: 3, Pages: 513-520, Published: DEC 2016
Popis: This study aimed to assess the immunoexpression of cell proliferation markers (Ki-67 and Mcm-2) in oral tongue cancer, correlating it with patients' age and prognostic indicators. Sample was composed of 22 cases under 40 years and 22 over 50 years of age. Clinical staging and histological grade of malignancy were obtained. Cell proliferation was evaluated through labeling indices. Statistical analysis was performed (p0.05). Mean Ki-67-LI in young and older patients was 42.4 % and 44.15 %, respectively (p>0.05). Mean Mcm-2-LI was higher in older (63.6 %) than in young patients (55.75 %) (p 0,05). La media de Ki-67-LI en pacientes jóvenes y mayores fue 42,4% y 44,15%, respectivamente (p> 0,05). La media de Mcm-2-LI fue mayor en pacientes mayores (63,6 %) que en pacientes jóvenes (55,75 %) (p
Databáze: OpenAIRE