| Autor: |
Beltrán, Marcelo A, Barría, Carlos, Contreras, Mario A, Wilson, Christian S, Cruces, Karina S |
| Jazyk: |
Spanish; Castilian |
| Rok vydání: |
2009 |
| Předmět: |
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| Zdroj: |
Revista médica de Chile, Volume: 137, Issue: 9, Pages: 1197-1200, Published: SEP 2009 |
| Popis: |
Neurofibromatosis Type 1 (NF1) is an autosomic dominant condition affecting the central nervous systema and presenting a disposition towards development of gastrointestinal stromal tumors (GIST). We report a 38year-old female patient with neurofibromatosis type 1 that required emergency surgery due to a perforated GIST originating in the fourth duodenal portion. The GIST, and the fourth duodenal portion, were excised and a primary duodenum-jejunal anastomosis was performed. The pathological study showed a partially necrotic solid-cystic tumor with 1 to 2 mitoses per 50-high-power fields. The cells stained positively to CD 117, CD34 and Desmin, and were negative to S-100, Vimentin, and Smooth Muscle a-Actin. The patient is currently asymptomatic and under follow-up during the last 11 months after surgery (Rev Méd Chile 2009; 137:1197-200). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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