| Autor: |
Schinor, Elisandra Cristina, Salvador, Marcos José, Tomaz, José Carlos, Pral, Elizabeth Mieko Furusho, Alfieri, Silvia Celina, Albuquerque, Sérgio de, Ito, Izabel Yoko, Dias, Diones Aparecida |
| Jazyk: |
angličtina |
| Rok vydání: |
2006 |
| Předmět: |
|
| Zdroj: |
Revista Brasileira de Ciências Farmacêuticas, Volume: 42, Issue: 1, Pages: 83-90, Published: MAR 2006 |
| Popis: |
Crude extracts of Chresta exsucca were investigated for their in vitro trypanocidal, leishmanicidal, antibacterial and antifungal activities. Trypomastigote forms of Trypanosoma cruzi, amastigote-like forms of Leishmania amazonensis and twenty strains of microorganisms including Gram-positive and Gram-negative bacteria and yeasts were utilized in the bioassays. The best results were found for the leishmanicidal activity. The chemical composition of hexanic and ethanolic extracts of this species was determinate using chromatographic techniques as HRGC and HPLC-ESI-MS, respectively. Steroids, triterpenes and flavonoids were identified. As atividades tripanocida, leishmanicida, antibacteriana e antifungica dos extratos brutos de Chresta exsucca foram investigadas. Formas tripomastigotas do Trypanosoma cruzi, formas amastigotas de Leishmania amazonensis e vinte cepas de microrganismos, incluindo bactérias Gram-positivas, Gram-negativas e leveduras, foram utilizadas nos ensaios biológicos. Os melhores resultados foram obtidos para a atividade leishmanicida. A composição química dos extratos hexânicos e etanólicos dessa espécie foi determinada empregando-se técnicas cromatográficas como HRGC e HPLC-ESI-MS, respectivamente. Esteróides, triterpenos e flavonóides foram identificados. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
