| Autor: |
França, Hildegardo Seibert, Kuster, Ricardo Machado, Rito, Priscila da Nóbrega, Oliveira, Adriana Passos de, Teixeira, Lenise Arneiro, Rocha, Leandro |
| Jazyk: |
portugalština |
| Rok vydání: |
2009 |
| Předmět: |
|
| Zdroj: |
Química Nova, Volume: 32, Issue: 5, Pages: 1103-1106, Published: 2009 |
| Popis: |
Three phloroglucinols were obtained from Hypericum brasiliense: japonicine A (1), isouliginosin B (2) and uliginosin B (3). Bioautography and disk diffusion methods were used to determine antibacterial activity of the hexanic extract. Strains of the Coagulase Negative Staphylococcus and American Methicillin Resistant Staphylococcus aureus clones showed a growth inhibition zone ranging from 10 to 12 mm and 7 to 15 mm, respectively. Minimal inhibitory concentration (MIC) values were used to measure antistaphylococcal activity for all phloroglucinols. Isouliginosin B and uliginosin B presented MIC values of 1.5 and 3.0 µg/mL, respectively, while japonicine A displayed MIC value of 50.0 µg/mL. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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