Impact of Omega-3 Supplementation with Alpha-Linolenic Acid on Neuronal Cell Fatty Acid Status

Autor: Densel, Owen
Rok vydání: 2016
Zdroj: College of Health and Human Sciences Honors Program Undergraduate Theses
Popis: A method of treating retinoic acid differentiated SH-SY5Y neuroblastoma cells with alpha-linolenic acid (ALA) in the free acid form has been developed in order to examine impacts of such supplementation on fatty acid composition of cells and on functional outcomes. Through Bovine Serum Albumin: ALA conjugation, an ALA treatment media was created and compared to the stock media which contained no detectible amounts of ALA. Results from fatty acid analysis of the control cells (n=3) and ALA-supplemented cells (n=3) showed a significantly higher content of ALA in ALA-supplemented cells (37.35 mol%) compared to control cells (
Databáze: OpenAIRE