Vitamin D3 Supplementation Increases Spine Bone Mineral Density in Adolescents and Young Adults With Human Immunodeficiency Virus Infection Being Treated With Tenofovir Disoproxil Fumarate: A Randomized, Placebo-Controlled Trial

Autor: Havens, Peter L, Stephensen, Charles B, Van Loan, Marta D, Schuster, Gertrud U, Woodhouse, Leslie R, Flynn, Patricia M, Gordon, Catherine M, Pan, Cynthia G, Rutledge, Brandy, Harris, D Robert, Price, Georgine, Baker, Alyne, Meyer, William A, Wilson, Craig M, Hazra, Rohan, Kapogiannis, Bill G, Mulligan, Kathleen, Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) 109 Study Team
Rok vydání: 2018
Předmět:
Zdroj: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol 66, iss 2
ISSN: 0175-1646
Popis: BackgroundTenofovir disoproxil fumarate (TDF) decreases bone mineral density (BMD). We hypothesized that vitamin D3 (VITD3) would increase BMD in youth receiving TDF.MethodsThis was a randomized, double-blind, placebo-controlled trial of directly observed VITD3 vs placebo every 4 weeks for 48 weeks in youth aged 16-24 years with HIV, RNA load
Databáze: OpenAIRE