Short Communication: Coronary Heart Disease Risk by Framingham Risk Score in Hepatitis C and HIV/Hepatitis C-Coinfected Persons
| Autor: | Chew, Kara W, Bhattacharya, Debika, McGinnis, Kathleen A, Horwich, Tamara B, Tseng, Chi-Hong, Currier, Judith S, Butt, Adeel A, ERCHIVES (Electronically Retrieved Cohort of HCV Infected Veterans) Study |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Chronic Liver Disease and Cirrhosis Clinical Sciences HIV Infections Coronary Disease Cardiovascular Risk Assessment ERCHIVES (Electronically Retrieved Cohort of HCV Infected Veterans) Study Hepatitis Substance Misuse Hepatitis - C Clinical Research Virology Humans Chronic Heart Disease - Coronary Heart Disease Aged Coinfection Prevention Liver Disease Middle Aged Hepatitis C Heart Disease Infectious Diseases Emerging Infectious Diseases Good Health and Well Being Case-Control Studies HIV/AIDS Drug Abuse (NIDA only) Digestive Diseases Infection |
| Zdroj: | AIDS research and human retroviruses, vol 31, iss 7 |
| Popis: | We compared the Framingham risk score (FRS) for 10-year coronary heart disease (CHD) risk in age- and race-matched hepatitis C virus (HCV)-infected and HCV-uninfected persons: 114,073 HCV-infected (111,436 HCV-monoinfected and 2,637 HIV/HCV-coinfected) and 122,996 HCV-uninfected (121,380 HIV and HCV-uninfected and 1,616 HIV-monoinfected) males without cardiovascular disease, diabetes, or hepatitis B. In unadjusted analyses, FRS was similar between the HCV-infected and HCV-uninfected groups [median (interquartile range, IQR) risk points 13 (10-14) vs. 13 (10-14), p=0.192]. Cholesterol levels were lower and current smoking more prevalent in the HCV groups (both HCV and HIV/HCV) compared with the uninfected groups (p |
| Databáze: | OpenAIRE |
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