Decoupling of the PI3K pathway via mutation necessitates combinatorial treatment in HER2+ breast cancer

Autor: Collisson, Eric, Korkola, JE, Collisson, EA, Heiser, L, Oates, C, Bayani, N, Itani, S, Esch, A, Thompson, W, Griffith, OL, Wang, NJ
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Collisson, Eric; Korkola, JE; Collisson, EA; Heiser, L; Oates, C; Bayani, N; et al.(2015). Decoupling of the PI3K pathway via mutation necessitates combinatorial treatment in HER2+ breast cancer. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/2c4652pn
Popis: © 2015 Korkola et al.We report here on experimental and theoretical efforts to determine how best to combine drugs that inhibit HER2 and AKT in HER2+ breast cancers. We accomplished this by measuring cellular and molecular responses to lapatinib
Databáze: OpenAIRE