A compact, in vivo screen of all 6-mers reveals drivers of tissue-specific expression and guides synthetic regulatory element design

Autor: Ahituv, Nadav, Pollard, Katherine, Smith, RP, Riesenfeld, SJ, Holloway, AK, Li, Q, Murphy, KK, Feliciano, NM, Orecchia, L, Oksenberg, N, Pollard, KS
Jazyk: angličtina
Rok vydání: 2013
Zdroj: Ahituv, Nadav; Pollard, Katherine; Smith, RP; Riesenfeld, SJ; Holloway, AK; Li, Q; et al.(2013). A compact, in vivo screen of all 6-mers reveals drivers of tissue-specific expression and guides synthetic regulatory element design. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/4rx601p6
Popis: Background: Large-scale annotation efforts have improved our ability to coarsely predict regulatory elements throughout vertebrate genomes. However, it is unclear how complex spatiotemporal patterns of gene expression driven by these elements emerge from t
Databáze: OpenAIRE