Prevalence of and risk factors for anal high-risk HPV among HIV-negative and HIV-positive MSM and transgender women in three countries at South-East Asia
| Autor: | Somia, I Ketut Agus, Teeratakulpisarn, Nipat, Jeo, Wifanto S, Yee, Ilias A, Pankam, Tippawan, Nonenoy, Siriporn, Trachuntong, Deondara, Mingkwanrungrueng, Pravit, Sukmawati, Made Dewi D, Ramautarsing, Reshmie, Nilasari, Hanny, Hairunisa, Nany, Azwa, Iskandar, Yunihastuti, Evy, Merati, Tuti P, Phanuphak, Praphan, Palefsky, Joel, Phanuphak, Nittaya, ANSAP Study Group |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male transgender women ANSAP Study Group Clinical Trials and Supportive Activities Anal high-risk HPV Anal Canal HIV Infections Sexual and Gender Minorities (SGM/LGBT*) Transgender Persons Sexual and Gender Minorities Risk Factors Clinical Research HIV Seronegativity HIV Seropositivity Behavioral and Social Science Prevalence Humans Prospective Studies MSM HIV-positive Papillomaviridae Cancer Prevention Papillomavirus Infections Malaysia virus diseases Middle Aged Thailand CD4 Lymphocyte Count Infectious Diseases Good Health and Well Being Indonesia Sexually Transmitted Infections HIV/AIDS Female Infection |
| Zdroj: | Medicine, vol 97, iss 10 |
| Popis: | This study aimed to assess the prevalence of and associated risk factors for anal high-risk human papillomavirus (hr-HPV) infection among men who have sex with men (MSM) and transgender women (TGW) in Indonesia, Thailand, and Malaysia.This was baseline data from a prospective cohort study with clinic sites in Jakarta and Bali (Indonesia), Bangkok (Thailand), and Kuala Lumpur (Malaysia).MSM and TGW aged 18 years and older from Indonesia, Thailand, and Malaysia were enrolled. Demographic and behavioral characteristics were assessed, and anal samples were collected for HPV genotyping. Multivariate logistic regression models were used to assess risk factors for anal hr-HPV overall and among HIV-positive participants.A total of 392 participants were enrolled, and 48 were TGW. As many as 245 were HIV-positive, and 78.0% of the participants were on combination antiretroviral therapy (cART). Median CD4 count was 439 cells/mm and 68.2% had undetectable HIV-RNA. HIV-positive participants had significantly more hr-HPV compared to HIV-negative participants (76.6% vs 53.5%, P |
| Databáze: | OpenAIRE |
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