| Autor: |
Huffman, Jennifer E, de Vries, Paul S, Morrison, Alanna C, Sabater-Lleal, Maria, Kacprowski, Tim, Auer, Paul L, Brody, Jennifer A, Chasman, Daniel I, Chen, Ming-Huei, Guo, Xiuqing, Lin, Li-An, Marioni, Riccardo E, Müller-Nurasyid, Martina, Yanek, Lisa R, Pankratz, Nathan, Grove, Megan L, de Maat, Moniek PM, Cushman, Mary, Wiggins, Kerri L, Qi, Lihong, Sennblad, Bengt, Harris, Sarah E, Polasek, Ozren, Riess, Helene, Rivadeneira, Fernando, Rose, Lynda M, Goel, Anuj, Taylor, Kent D, Teumer, Alexander, Uitterlinden, André G, Vaidya, Dhananjay, Yao, Jie, Tang, Weihong, Levy, Daniel, Waldenberger, Melanie, Becker, Diane M, Folsom, Aaron R, Giulianini, Franco, Greinacher, Andreas, Hofman, Albert, Huang, Chiang-Ching, Kooperberg, Charles, Silveira, Angela, Starr, John M, Strauch, Konstantin, Strawbridge, Rona J, Wright, Alan F, McKnight, Barbara, Franco, Oscar H, Zakai, Neil, Mathias, Rasika A, Psaty, Bruce M, Ridker, Paul M, Tofler, Geoffrey H, Völker, Uwe, Watkins, Hugh, Fornage, Myriam, Hamsten, Anders, Deary, Ian J, Boerwinkle, Eric, Koenig, Wolfgang, Rotter, Jerome I, Hayward, Caroline, Dehghan, Abbas, Reiner, Alex P, O'Donnell, Christopher J, Smith, Nicholas L |
| Rok vydání: |
2015 |
| Předmět: |
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| Zdroj: |
Blood, vol 126, iss 11 |
| Popis: |
Fibrinogen, coagulation factor VII (FVII), and factor VIII (FVIII) and its carrier von Willebrand factor (vWF) play key roles in hemostasis. Previously identified common variants explain only a small fraction of the trait heritabilities, and additional variations may be explained by associations with rarer variants with larger effects. The aim of this study was to identify low-frequency (minor allele frequency [MAF] ≥0.01 and |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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