In vivo comparison of tantalum, tungsten, and bismuth enteric contrast agents to complement intravenous iodine for double-contrast dual-energy CT of the bowel
| Autor: | Rathnayake, Samira, Mongan, John, Torres, Andrew S, Colborn, Robert, Gao, Dong-Wei, Yeh, Benjamin M, Fu, Yanjun |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
tantalum
tungsten Medical Biotechnology Biomedical Engineering Contrast Media contrast agent Small dual-energy CT Intestine X-Ray Computed Gastrointestinal Tract Medicinal and Biomolecular Chemistry Nuclear Medicine & Medical Imaging small bowel bismuth Animals Biomedical Imaging Rabbits Digestive Diseases Tomography Iodine CT enterography |
| Zdroj: | Contrast media & molecular imaging, vol 11, iss 4 |
| Popis: | To assess the ability of dual-energy CT (DECT) to separate intravenous contrast of bowel wall from intraluminal contrast, we scanned 16 rabbits on a clinical DECT scanner: n = 3 using only iodinated intravenous contrast, and n = 13 double-contrast enhanced scans using iodinated intravenous contrast and experimental enteric non-iodinated contrast agents in the bowel lumen (five bismuth, four tungsten, and four tantalum based). Representative image pairs from conventional CT images and DECT iodine density maps of small bowel (116 pairs from 232 images) were viewed by four abdominal imaging attending radiologists to independently score each comparison pair on a visual analog scale (-100 to +100%) for (1) preference in small bowel wall visualization and (2) preference in completeness of intraluminal enteric contrast subtraction. Median small bowel wall visualization was scored 39 and 42 percentage points (95% CI 30-44% and 36-45%, both p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|