Urine creatinine-based estimates of fat-free mass in community-dwelling older persons: The Rancho Bernardo study

Autor: Jassal, SK, Wassel, CL, Laughlin, GA, Barrett-Connor, E, Rifkin, DE, Ix, JH
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Jassal, SK; Wassel, CL; Laughlin, GA; Barrett-Connor, E; Rifkin, DE; & Ix, JH. (2015). Urine creatinine-based estimates of fat-free mass in community-dwelling older persons: The Rancho Bernardo study. Journal of Renal Nutrition, 25(2), 97-102. doi: 10.1053/j.jrn.2014.07.005. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/40k629b0
Popis: © 2015 .Objectives: To determine whether a previously developed and externally validated equation using common variables (demographics and weight) that are important determinants of muscle mass to estimate 24-hour urine creatinine excretion rate (eCER) is associated with muscle mass and whether spot urine creatinine (UCr) provides similar estimates of muscle mass. Design: Observational cross-sectional cohort study. Setting: The Rancho Bernardo Study, San Diego, California. Subjects: A total of 1,371 Caucasian, middle class, community-dwelling older adults. Intervention: Morning spot UCr and fat-free mass (FFM) by dual-energy x-ray absorptiometry were measured. eCER was calculated: eCER (mg/day)=879.89+12.51 × weight (kilogram) - 6.19 × age+34.51 if black - 379.42 if female. Pearson correlation coefficients and linear regression were used to determine strengths of association of eCER and spot UCr with FFM. Results: Mean age was 70years, and 58% were women. eCER was strongly correlated with FFM (. r=0.95, P
Databáze: OpenAIRE