Borrelia miyamotoi sensu lato seroreactivity and seroprevalence in the northeastern United States
| Autor: | Krause, Peter J, Narasimhan, Sukanya, Wormser, Gary P, Barbour, Alan G, Platonov, Alexander E, Brancato, Janna, Lepore, Timothy, Dardick, Kenneth, Mamula, Mark, Rollend, Lindsay, Steeves, Tanner K, Diuk-Wasser, Maria, Usmani-Brown, Sahar, Williamson, Phillip, Sarksyan, Denis S, Fikrig, Erol, Fish, Durland, Tick Borne Diseases Group |
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| Rok vydání: | 2014 |
| Předmět: |
Male
Tick Borne Diseases Group Clinical Sciences tick-borne disease spirochete Borrelia miyamotoi sensu lato Microbiology Antibodies ticks Seroepidemiologic Studies New England parasitic diseases Humans Lyme disease bacteria Borrelia miyamotoi infection northeastern United States seroprevalence Borrelia Bacterial Middle Aged bacterial infections and mycoses United States New York State seroreactivity Medical Microbiology Immunoglobulin G Borrelia burgdorferi relapsing fever Public Health and Health Services Female Borrelia Infections geographic locations |
| Zdroj: | Emerging infectious diseases, vol 20, iss 7 |
| Popis: | Borrelia miyamotoi sensu lato, a relapsing fever Borrelia sp., is transmitted by the same ticks that transmit B. burgdorferi (the Lyme disease pathogen) and occurs in all Lyme disease-endemic areas of the United States. To determine the seroprevalence of IgG against B. miyamotoi sensu lato in the northeastern United States and assess whether serum from B. miyamotoi sensu lato-infected persons is reactive to B. burgdorferi antigens, we tested archived serum samples from area residents during 1991-2012. Of 639 samples from healthy persons, 25 were positive for B. miyamotoi sensu lato and 60 for B. burgdorferi. Samples from ≈10% of B. miyamotoi sensu lato-seropositive persons without a recent history of Lyme disease were seropositive for B. burgdorferi. Our results suggest that human B. miyamotoi sensu lato infection may be common in southern New England and that B. burgdorferi antibody testing is not an effective surrogate for detecting B. miyamotoi sensu lato infection. |
| Databáze: | OpenAIRE |
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