Autor: |
Renslo, Adam, Walter, Peter, Sidrauski, C, Tsai, JC, Kampmann, M, Hearn, BR, Vedantham, P, Jaishankar, P, Sokabe, M, Mendez, AS, Newton, BW, Tang, EL |
Jazyk: |
angličtina |
Rok vydání: |
2015 |
Zdroj: |
Renslo, Adam; Walter, Peter; Sidrauski, C; Tsai, JC; Kampmann, M; Hearn, BR; et al.(2015). Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes theintegrated stress response. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/1n22h5zs |
Popis: |
© 2015, eLife. All rights reserve.The general translation initiation factor eIF2 is a major translational control point. Multiple signaling pathways in the integrated stress response phosphorylate eIF2 serine-51, inhibiting nucleotide exchange by eIF2B. IS |
Databáze: |
OpenAIRE |
Externí odkaz: |
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