A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition

Autor: Maher, Jacquelyn, Wei, K, Piecewicz, SM, McGinnis, LM, Taniguchi, CM, Wiegand, SJ, Anderson, K, Chan, CWM, Mulligan, KX, Kuo, D, Yuan, J
Jazyk: angličtina
Rok vydání: 2013
Zdroj: Maher, Jacquelyn; Wei, K; Piecewicz, SM; McGinnis, LM; Taniguchi, CM; Wiegand, SJ; et al.(2013). A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/6sw8z39m
Popis: Insulin initiates diverse hepatic metabolic responses, including gluconeogenic suppression and induction of glycogen synthesis and lipogenesis. The liver possesses a rich sinusoidal capillary network with a higher degree of hypoxia and lower gluconeogenesi
Databáze: OpenAIRE