Management and Early Outcomes of Neonates Born to Women with SARS-CoV-2 in 16 U.S. Hospitals
| Autor: | Congdon, Jayme L, Kair, Laura R, Flaherman, Valerie J, Wood, Kelly E, LoFrumento, Mary Ann, Nwaobasi-Iwuh, Eberechi, Phillipi, Carrie A, Better Outcomes through Research for Newborns (BORN) Network |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Term Birth breastfeeding Clinical Sciences SARS CoV-2 Gestational Age Reproductive health and childbirth Low Birth Weight and Health of the Newborn Vaccine Related 7.3 Management and decision making Paediatrics and Reproductive Medicine Preterm Clinical Research Pregnancy newborn Biodefense Neonatal Infant Mortality Humans nursery Obstetrics & Reproductive Medicine Premature Lung Pediatric Health Services Needs and Demand mother-infant dyad Better Outcomes through Research for Newborns (BORN) Network Prevention Infectious Pregnancy Outcome Infant COVID-19 Perinatal Period - Conditions Originating in Perinatal Period United States Pregnancy Complications Hospitalization Intensive Care Units Emerging Infectious Diseases Good Health and Well Being Breast Feeding Infectious Diseases Practice Guidelines as Topic Premature Birth Female Management of diseases and conditions Guideline Adherence Patient Safety neonate |
| Zdroj: | American journal of perinatology, vol 38, iss 6 |
| Popis: | ObjectiveThere is a paucity of evidence to guide the clinical care of late preterm and term neonates born to women with perinatal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The objective of this case series is to describe early neonatal outcomes and inpatient management in U.S. hospitals.Study designWe solicited cases of mother-infant dyads affected by novel coronavirus disease 2019 (COVID-19) from the Better Outcomes through Research for Newborns (BORN) Network members. Using a structured case template, participating sites contributed deidentified, retrospective birth hospitalization data for neonates ≥35 weeks of gestation at birth with mothers who tested positive for SARS-CoV-2 before delivery. We describe demographic and clinical characteristics, clinical management, and neonatal outcomes.ResultsSixteen U.S. hospitals contributed 70 cases. Birth hospitalizations were uncomplicated for 66 (94%) neonates in which 4 (6%) required admission to a neonatal intensive care unit. None required evaluation or treatment for infection, and all who were tested for SARS-CoV-2 were negative (n = 57). Half of the dyads were colocated (n = 34) and 40% directly breastfed (n = 28). Outpatient follow-up data were available for 13 neonates, all of whom remained asymptomatic.ConclusionIn this multisite case series of 70 neonates born to women with SARS-CoV-2 infection, clinical outcomes were overall good, and there were no documented neonatal SARS-CoV-2 infections. Clinical management was largely inconsistent with contemporaneous U.S. COVID-19 guidelines for nursery care, suggesting concerns about the acceptability and feasibility of those recommendations. Longitudinal studies are urgently needed to assess the benefits and harms of current practices to inform evidence-based clinical care and aid shared decision-making.Key points· Birth hospitalizations were uncomplicated for late preterm and term infants with maternal COVID-19.. · Nursery management of dyads affected by COVID-19 varied between hospitals.. · Adherence to contemporaneous U.S. clinical guidelines for nursery care was low.. · Breastfeeding rates were lower for dyads roomed separately than those who were colocated.. |
| Databáze: | OpenAIRE |
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