A high throughput screen identifies potent and selective inhibitors to human epithelial 15-lipoxygenase-2

Autor: Jacobson, Matthew, Jameson, JB, Kantz, A, Schultz, L, Kalyanaraman, C, Jacobson, MP, Maloney, DJ, Jadhav, A, Simeonov, A, Holman, TR
Jazyk: angličtina
Rok vydání: 2014
Zdroj: Jacobson, Matthew; Jameson, JB; Kantz, A; Schultz, L; Kalyanaraman, C; Jacobson, MP; et al.(2014). A high throughput screen identifies potent and selective inhibitors to human epithelial 15-lipoxygenase-2. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/8cq899v6
Popis: Lipoxygenase (LOX) enzymes catalyze the hydroperoxidation of arachidonic acid and other polyunsaturated fatty acids to hydroxyeicosatetraenoic acids with varying positional specificity to yield important biological signaling molecules. Human epithelial 15
Databáze: OpenAIRE